1.      Murrell, S., Wu, S.C.* and Butler, M. (2011). “Review of dengue virus and the development of a vaccine.” Biotechnology Advances 29(2): 239-247. (*corresponding author).

2.      Hu, A.Y.C., Tseng, Y.F., Weng, T.C., Liao, C.C., Wu, J., Chou, A.H., Chao, H.J., Gu, A.N., Chen, J., Lin, S.C., Hsiao, C.H., Wu, S.C. and Chong, P. (2011). “Production of Inactivated Influenza H5N1 Vaccines from MDCK Cells in Serum-Free Medium.” PLOS One 6(1).

3.      Cheng, C.S., Chen, W.T., Lee, L.H., Chen, Y.W., Chang, S.Y., Lyu, P.C. and Yin, H.S. (2011). “Structural and functional comparison of cytokine interleukin-1 beta from chicken and human.” Molecular Immunology 48(6-7): 947-955.

4.      Liao, Y.C., Huang, T.W., Chen, F.C., Charusanti, P., Hong, J.S.J., Chang, H.Y., Tsai, S.F., Palsson, B.O. and Hsiung, C.A. (2011). “An Experimentally Validated Genome-Scale Metabolic Reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228.” Journal of Bacteriology 193(7): 1710-1717.

5.      Hsu, F.Y., Chou, L.F., Hor, L.I. and Chang, H.Y.* (2011). “A human single-chain variable fragment targeting to Vibrio vulnificus RtxA toxin.” Journal of Microbiological Methods 84(1): 94-100. (*corresponding author).

6.      Chen, F.J., Chan, C.H., Huang, Y.J., Liu, K.L., Peng, H.L., Chang, H.Y., Liou, G.G., Yew, T.R., Liu, C.H., Hsu, K.Y. and Hsu, L. (2011). “Structural and Mechanical Properties of Klebsiella pneumoniae Type 3 Fimbriae.” Journal of Bacteriology 193(7): 1718-1725.

7.      Kang, C.C., Chuang, Y.J., Tung, K.C., Cho, C.C., Tang, C.Y., Peng, S.C. and Wong, D.S. (2011). “A Genetic Algorithm-based Boolean Delay Model of Intracellular Signal Transduction in Inflammation.” BMC Bioinformatics 12(Suppl 1): S17.

1.      Yu, H.Y., Huang, K.C., Yip, B.S., Tu, C.H., Chen, H.L., Cheng, H.T. and Cheng, J.W.* (2010). “Rational design of tryptophan-rich antimicrobial peptides with enhanced antimicrobial activities and specificities.” Chembiochem 11: 2273-2282. (*corresponding author).

2.      Chen, H.L., Her, S.Y. Huang, K.C., Cheng, H.T., Wu, C.W., Wu, S.C. and Cheng, J.W.* (2010). “Identification of a Heparin Binding Peptide From the Japanese Encephalitis Virus Envelope Protein.” Biopolymers 94(3): 331-338.

3.      Pan, Y.S., Wei, H.J., Chang, C.C., Lin, C.H., Wei, T.S., Wu, S.C.* and Chang, D. K. (2010). “Construction and Characterization of Insect Cell-Derived Influenza VLP: Cell Binding, Fusion, and EGFP Incorporation.” Journal of Biomedicine and Biotechnology 506363. (*corresponding author).

4.      Liu, W.C., Lin, S.C., Yu, Y.L., Chu, C.L. and Wu, S.C.* (2010). “Dendritic Cell Activation by Recombinant Hemagglutinin Proteins of H1N1 and H5N1 Influenza A Viruses.” Journal of Virology 84(22): 12011-12017. (*corresponding author).

5.      Lin, Y. J., Peng, J.G. and Wu, S.C.* (2010). “Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein.” Journal of Biomedical Science 17: 39. (*corresponding author).

6.      Lee, T.S., Pan, C.C., Peng, C.C., Kou, Y.R., Chen, C.Y., Ching, L.C., Tsai, T.H., Chen, S.F., Lyu, P.C. and Shyue, S.K. (2010). “Anti-Atherogenic Effect of Berberine on LXR alpha-ABCA1-Dependent Cholesterol Efflux in Macrophages.” Journal of Cellular Biochemistry 111(1): 104-110.

7.      Lin, S.C., Leng, C.H. and Wu, S.C.* (2010). “Generating Stable Chinese Hamster Ovary Cell Clones to Produce a Truncated SARS-CoV Spike Protein for Vaccine Development.” Biotechnology Progress 26(6): 1733-1740. (*corresponding author).

8.      Hsu, T.C., Lan, J.L., Kao, S.H., Li, S.L., Liu, Y.C., Huang, C.Y. and Tzang, B.S. (2010). “Identification of an Autoantibody against the Proliferating Cell Nuclear Antigen from a Patient with Systemic Lupus Erythematosus.” Chinese Journal of Physiology 53(1): 11-18.

9.      Chen, H. L., Her, S.Y., Huang, K.C., Cheng, H.T., Wu, C.W., Wu, S.C. and Cheng, J. W. (2010). “Identification of a Heparin Binding Peptide From the Japanese Encephalitis Virus Envelope Protein.” Biopolymers 94(3): 331-338.

10. Chang, Y. F., Wang, S.F., Huang, J.C., Su, L.C., Yao, L., Li, Y.C., Wu, S.C., Chen, Y.M.A., Hsieh, J.P. and Chou, C. (2010). “Detection of swine-origin influenza A (H1N1) viruses using a localized surface plasmon coupled fluorescence fiber-optic biosensor.” Biosensors & Bioelectronics 26(3): 1068-1073.

11. Peng, S.C., Wong, D.S.H., Tung, K.C., Chen, Y.Y., Chao, C.C., Peng, C.H., Chuang, Y.J.* and Tang, C.Y. (2010). “Computing modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappa B signaling-induced gene expression responses in inflammation.” BMC Bioinformatics 11: 308. (*corresponding author).

12. Chang, H.T., Tseng, L.J., Hung, T.J., Kao, B.T., Lin, W.Y., Fan, T.C., Chang, M.D.T. and Pai, T.W. (2010). “Inhibition of the interactions between eosinophil cationic protein and airway epithelial cells by traditional Chinese herbs.” BMC System Biol. 4(Suppl 2): S8.

13. Yang, S.K., Wang, Y.C., Chao, C.C., Chuang, Y.J., Lan, C.Y. and Chen, B.S. (2010). “Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNF alpha-induced inflammatory responses.” BMC Medical Genomics 3: 19.

14. Chao, C.C., Hsu, P.C., Jen, C.F., Chen, I.H., Wang, C.H., Chan, H.C., Tsai, P.W., Tung, K.C., Wang, C.H., Lan, C.Y., Chuang, Y.J.* (2010). “Zebrafish as a Model Host for Candida albicans Infection.” Infection and Immunity 78(6): 2512-2521. (*corresponding author).

15. Yan, K.H., Yao, C.J., Chang, H.Y., Lai, G.M., Cheng, A.L. and Chuang, S.E. (2010). “The Synergistic Anticancer Effect of Troglitazone Combined With Aspirin Causes Cell Cycle Arrest and Apoptosis in Human Lung Cancer Cells.” Molecular Carcinogenesis 49(3): 235-246.

16. Lee, H.J., Ho, M.R., Bhuwan, M., Hsu, C.Y., Huang, M.S., Peng, H.L. and Chang, H.Y.* (2010). “Enhancing ATP-based bacteria and biofilm detection by enzymatic pyrophosphate regeneration.” Analytical Biochemistry 399(2): 168-173.

17. Hsu, C.L., Shiung, Y.Y., Lin, B.L., Chang, H.Y. and Chang, T.W. (2010). “Accumulated immune complexes of IgE and omalizumab trap allergens in an in vitro model.” International Immunopharmacology 10(4): 533-539.

18. Cheng, H.Y., Chen, Y.S., Wu, C.Y., Chang, H.Y., Lai, Y.C. and Peng, H.L. (2010). “RmpA Regulation of Capsular Polysaccharide Biosynthesis in Klebsiella pneumoniae CG43.” Journal of Bacteriology 192(12): 3144-3158.

19. Chen, J.B., Wu, P.C., Hung, A.F.H., Chu, C.Y., Tsai, T.F., Yu, H.M., Chang, H.Y. and Chang, T.W. (2010). “Unique Epitopes on C epsilon mX in IgE-B Cell Receptors Are Potentially Applicable for Targeting IgE-Committed B Cells.” Journal of Immunology 184(4): 1748-1756.

20. Chen, C.J., Krishna, R.V., Tsai, C.C., Wu, W.H., Chao, L.K., Hwang, K.H., Chien, C.M., Chang, H.Y. and Chen, S.T. (2010). “Structure and functions of gamma-dodecalactone isolated from Antrodia camphorata for NK cell activation.” Bioorganic & Medicinal Chemistry 18(18): 6896-6904.

21. Lin, Y.M., Wu, S.J., Chang, T.W., Wang, C.F., Suen, C.S., Hwang, M.J., Chang, M.D.T., Chen, Y.T. and Liao, Y.D. (2010). “Outer Membrane Protein I of Pseudomonas aeruginosa Is a Target of Cationic Antimicrobial Peptide/Protein.” Journal of Biological Chemistry 285(12): 8985-8994.

1.          Yip, B.S., Chen, H.L., Cheng, H.T., Wu, J.M. and Cheng, J.W. (2009). “Solution Structure and Model Membrane Interactions of P-113, a Clinically Active Antimicrobial Peptide Derived from Human Saliva.” Journal of the Chinese Chemical Society 56(5): 961-966.

2.          Wang, C.W., Yip, B.S., Cheng, H.T., Wang, A.H., Chen, H.L., Cheng, J.W. and Lo, H.J. (2009). “Increased potency of a novel D-beta-naphthylalanine-substituted antimicrobial peptide against fluconazole-resistant fungal pathogens.” Fems Yeast Research 9(6): 967-970.

3.          Tu, Y.C., Lu, M.C., Chiang, M.K., Huang, S.P., Peng, H.L., Chang, H.Y., Jan, M.S. and Lai, Y.C. (2009). “Genetic Requirements for Klebsiella pneumoniae-Induced Liver Abscess in an Oral Infection Model.” Infection and Immunity 77(7): 2657-2671.

4.          Chou, L.F., Peng, H.L., Yang, Y.C., Kuo, M.C. and Chang, H.Y.* (2009). “Localization and characterization of VVA0331, a 489-kDa RTX-like protein, in Vibrio vulnificus YJ016.” Archives of Microbiology 191(5): 441-450. (*corresponding author).

5.          Chen, Y.Y., Wu, C.C., Hsu, J.L., Peng, H.L., Chang, H.Y. and Yew, T.R. (2009). “Surface Rigidity Change of Escherichia coli after Filamentous Bacteriophage Infection.” Langmuir 25(8): 4607-4614.

6.          Chen, T.C., Chang, H.Y., Lin, P.F., Chern, J.H., Hsu, J.T.A., Chang, C.Y. and Shih, S.R. (2009). “Novel Antiviral Agent DTriP-22 Targets RNA-Dependent RNA Polymerase of Enterovirus 71.” Antimicrobial Agents and Chemotherapy 53(7): 2740-2747.

7.          Figueroa-Romero, C., Iniguez-Lluhi, J.A., Stadler, J., Chang, C.R., Arnoult, D., Keller, P.J., Hong, Y., Blackstone, C. and Feldman, E.L. (2009). “SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle.” Faseb Journal 23(11): 3917-3927.

8.          Wang, H.Y., Ho, P.C., Lan, C.Y. and Chang, M.D.T.* (2009). “Transcriptional Regulation of Human Eosinophil RNase2 by the Liver-Enriched Hepatocyte Nuclear Factor 4.” Journal of Cellular Biochemistry 106(2): 317-326. (*corresponding author).

1.      Weng, K.Y., Chou, N.J. and Cheng, J.W. (2008). “Triggering vacuum capillaries for pneumatic pumping and metering liquids in point-of-care immunoassays.” Lab on a Chip 8(7): 1216-1219.

2.      Huang, K.C., Lee, M.C., Wu, C.W., Huang, K.J., Lei, H.Y. and Cheng, J.W.* (2008). “Solution structure and neutralizing antibody binding studies of domain III of the dengue-2 virus envelope protein.” Proteins-Structure Function and Bioinformatics 70(3): 1116-1119. (*corresponding author).

3.      Cheng, H.T., Huang, K.C., Yu, H.Y., Gao, K.J., Zhao, X.X., Li, F., Town, J., Gordon, J.R. and Cheng, J.W.* (2008). “A new protocol for high-yield purification of recombinant human CXCL8((3-72))K11R/G31P expressed in Escherichia coli.” Protein Expression and Purification 61(1): 65-72. (*corresponding author).

4.      Chen, M.L., Adak, A.K., Yeh, N.C., Yang, W.B., Chuang, Y.J., Wong, C.H., Hwang, K.C., Hwu, J.R.R., Hsieh, S.L. and Lin, C.C. (2008). “Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation.” Angewandte Chemie-International Edition 47(45): 8627-8630.

5.      Chen, B.S., Yang, S.K., Lan, C.Y. and Chuang, Y.J. (2008). “A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining.” BMC Medical Genomics 1: 46.

6.      Chen, B.S., Chang, C.H. and Chuang, Y.J. (2008). “Robust model matching control of immune systems under environmental disturbances: Dynamic game approach.” Journal of Theoretical Biology 253(4): 824-837.

7.      Su, I.J., Wang, H.C., Wu, H.C. and Huang, W.Y. (2008). “Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection.” Journal of Gastroenterology and Hepatology 23(8 pt1): 1169-1174.

8.      Wu, S.C.*, Hong, W.W. and Liu, J. H. (2008). “Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells.” Vaccine 26(38): 4969-4974. (*corresponding author).

9.      Liu, C.C., Lee, S.C., Butler, M. and Wu, S.C. (2008). “High Genetic Stability of Dengue Virus Propagated in MRC-5 Cells as Compared to the Virus Propagated in Vero Cells.” PLOS One 3(3).

10. Hu, A.Y.C., Weng, T.C., Tseng, Y.F., Chen, Y.S., Wu, C.H., Hsiao, S., Chou, A.H., Chao, H.J., Gu, A., Wu, S.C., Chong, P. and Lee, M. S. (2008). “Microcarrier-based MDCK cell culture system for the production of influenza H5N1 vaccines.” Vaccine 26(45): 5736-5740.

11. Peng, T.Y., Lee, K.R. and Tarn, W.Y. (2008). “Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization.” Febs Journal 275(16): 4152-4163.

12. Lee, C.F., Ling, Z.Q., Zhao, T. and Lee, K.R.* (2008). “Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma.” World Journal of Gastroenterology 14(39): 6072-6077. (*corresponding author).

13. Liu, W.T., Lin, S.C., Chou, W.I., Liu, T.H., Pan, R.L., Tzou, D.L., Hua, T.E. and Chang, M.D.T.* (2008). “Identification and characterization of a novel fibril forming peptide in fungal starch binding domain.” Biochemical and Biophysical Research Communications 377(3): 966-970. (*corresponding author).

14. Huang, R.Y., Chang, H.T., Lan, C.Y., Pai, T.W., Wu, C.N., Ling, C.M. and Chang, M.D.T.* (2008). “Development and evaluation of a sensitive enzyme-linked oligonucleotide-sorbent assay for detection of polymerase chain reaction-amplified hepatitis C virus of genotypes 1-6.” Journal of Virological Methods 151(2): 211-216. (*corresponding author).

15. Fan, T.C., Fang, S.L., Hwang, C.S., Hsu, C.Y., Lu, X.A., Hung, S.C., Lin, S.C. and Chang, M.D.T.* (2008). “Characterization of molecular interactions between eosinophil cationic protein and heparin.” Journal of Biological Chemistry 283(37): 25468-25474. (*corresponding author).

16. Shu, A.C., Wu, C.C., Chen, Y.Y., Peng, H.L., Chang, H.Y. and Yew, T.R. (2008). “Evidence of DNA transfer through F-pilus channels during Escherichia coli conjugation.” Langmuir 24(13): 6796-6802.

17. Pan, Y.R., Vatsyayan, J., Chang, Y.S. and Chang, H.Y.* (2008). “Epstein-Barr virus latent membrane protein 2A upregulates UDP-glucose dehydrogenase gene expression via ERK and PI3K/Akt pathway.” Cellular Microbiology 10(12): 2447-2460.

18. Lu, Y.C., Chuang, Y.S., Chen, Y.Y., Shu, A.C., Hsu, H.Y., Chang, H.Y. and Yew, T.R. (2008). “Bacteria detection utilizing electrical conductivity.” Biosensors & Bioelectronics 23(12): 1856-1861.

19. Liu, Y.J., Yao, D.J., Lin, H.C., Chang, W.Y. and Chang, H.Y. (2008). “DNA ligation of ultramicro volume using an EWOD microfluidic system with coplanar electrodes.” Journal of Micromechanics and Microengineering 18(4): 7.

20. Liu, Y.J., Yao, D.J., Chang, H.Y., Liu, C.M. and Chen, C. (2008). “Magnetic bead-based DNA detection with multi-layers quantum dots labeling for rapid detection of Escherichia coli O157:H7.” Biosensors & Bioelectronics 24(4): 558-565.

21. Liu, K.L., Wu, C.C., Huang, Y.J., Peng, H.L., Chang, H.Y., Chang, P., Hsu, L. and Yew, T.R. (2008). “Novel microchip for in situ TEM imaging of living organisms and bio-reactions in aqueous conditions.” Lab on a Chip 8(11): 1915-1921.

22. Lee, H.J., Chang, H.Y., Venkatesan, N. and Peng, H.L. (2008). “Identification of amino acid residues important for the phosphomannose isomerase activity of Ps1B in Pseudomonas aeruginosa PAO1.” Febs Letters 582(23-24): 3479-3483.

23. Kuo, M.C., Chou, L.F. and Chang, H.Y.* (2008). “Evolution of exceptionally large genes in prokaryotes.” Journal of Molecular Evolution 66(4): 333-349. (*corresponding author).

24. Hsu, J.L., Peng, H.L. and Chang, H.Y.* (2008). “The ATP-binding motif in AcoK is required for regulation of acetoin catabolism in Klebsiella pneumoniae CG43.” Biochemical and Biophysical Research Communications 376(1): 121-127. (*corresponding author).

25. Hsu, J.L., Chen, H.C., Peng, H.L. and Chang, H.Y.* (2008). “Characterization of the histidine-containing phosphotransfer protein B-mediated multistep phosphorelay system in Pseudomonas aeruginosa PAO1.” Journal of Biological Chemistry 283(15): 9933-9944. (*corresponding author).

26. Chow, K.P.N., Wu, C.C., Chang, H.Y., Chang, C. and Chang, Y.S. (2008). “A simplified tumour model established via Epstein-Barr virus-encoded, nasopharyngeal carcinoma-derived oncogene latent membrane protein 1 in immunocompetent mice.” Laboratory Animals 42(2): 193-203.

27. Chen, T.C., Liu, S.C., Huang, P.N., Chang, H.Y., Chern, J.H. and Shih, S.R. (2008). “Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants.” Journal of Biomedical Science 15(3): 291-300.

28. Chang, J.H., Hocheng, H., Chang, H.Y. and Shih, A. (2008). “Metal removal rate of Thiobacillus thiooxidans without pre-secreted metabolite.” Journal of Materials Processing Technology 201(1-3): 560-564.